44
Blood Pressure Management
Table 13. FDA-Approved Drugs for Treatment of Hypertension
(cont'd)
Class Drug Usual dose, range (mg/d)*
Alternative agents (cont'd)
Direct vasodilators Hydralazine 100–200
Minoxidil 5–40
Dual endothelin receptor
antagonist
Aprocitentan 12.5
CCB, calcium channel blocker; CNS, central nervous system; CHD, coronary heart disease;
GFR, glomerular filtration rate; HFrEF, HF with reduced rejection fraction; and K+, potassium.
Modified with permission from Whelton et al. Copyright © 2018 American College of
Cardiolog y Foundation and American Heart Association, Inc. and with permission from
Chobanian et al. Copyright © 2003 American Heart Association, Inc.
