35
Section on
obstructive HCM
(See Figure 4)
If patient decompensates
while listed, evaluate for LVAD
(2a)
Evaluate for heart
transplant
(1)
Section on symptomatic
nonobstructive HCM
Recurrent ventricular
arrhythmias
Cardiac myosin inhibitor should be discontinued if LVEF <50% and can be restarted at a lower
dose if the LVEF recovers.
CRT indicates cardiac resynchronization therapy; EF, ejection fraction; GDMT, guideline-
directed management and therapy; HCM, hypertrophic cardiomyopathy; ICD, implantable
cardioverter-defibrillator; LBBB, le bundle branch block; LVAD, le ventricular assist device;
LVEF, le ventricular ejection fraction; and NYHA, New York Heart Association.
Reevaluation after GDMT
