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Hypertrophic Cardiomyopathy 2024

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20 Treatment 6.9. Individuals Who Are Genotype-Positive, Phenotype- Negative COR LOE Recommendations 1 B-NR 1. In individuals who are genotype-positive, phenotype-negative for HCM, serial clinical assessment, electrocardiography, and cardiac imaging are recommended at periodic intervals depending on age (every 1 to 2 years in children and adolescents and every 3 to 5 years in adults) and change in clinical status (Figure 1, Figure 2, Table 6). 2a B-NR 2. In individuals who are genotype-positive, phenotype-negative for HCM, participation in competitive sports of any intensity is reasonable. 3: No benefit B-NR 3. In individuals who are genotype-positive, phenotype-negative for HCM, ICD is not recommended for primary prevention.

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