16
Treatment
Figure 1. Recommended Evaluation and Testing for HCM
HCM Suspected or Family History of HCM
Diagnostic Testing
(ECG, Imaging, Genetics)
(See Figure 2 for details on genetic testing)
YES NO
Phenotype Negative
Further clinical or genetic
testing is not recommended
(3: No Benefit)
Family with
known P/LP
variant?
(See Figure 2 for
more detail)
Reassess variant
classification
(1)
1
YES, or Unknown
NO
Patient
has family
variant?
Variant downgraded to VUS
Variant = P/LP
* e interval may be extended, particularly in adult patients who remain stable aer
multiple evaluations.
3
4
Screening ECG and echo
(CMR if echo is inconclusive)
at the intervals in Table 6
(1)
5
