25
Indications Other considerations
Acute agitation with psychosis
Agitation not responding to BZDs
Toxic psychosis
Consider atypical or newer generation
antipsychotics as alternatives
Consider risk of QT prolongation
Anxiety or agitation with psychotic features
Stimulant-induced psychosis
Stimulant-induced sleep derangements
Consider risk of QT prolongation
For olanzapine, degree of symptoms to
balance need for PO vs. IM
For severe agitation as primary or secondary
agent
Rapid IM onset of action compared to
other agents
