AMDA Pocket Guidelines

Dementia Depression Delirium

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Appendices 44 Appendix B: Side-Effect Profile of Common Antipsychotic Medications 26 Agent Generic Name (Brand Name) QTc prolongation Anticholinergic effects CNS depression Dyslipidemia Hyperglycemia Orthostatic hypotension (falls) Weight gain Extrapyramidal Symptoms Increased Prolactin Aripiprazole (Abilify ® ) ± ± ± ± ± ± ± + + Clozapine (Clozaril ® ) ++ +++ +++ +++ +++ +++ +++ ± ± Haloperidol (Haldol ® ) + + +++ + + + ++ +++ +++ Olanzapine (Zyprexa ® ) + ++ ++ +++ +++ + +++ + ± Quetiapine (Seroquel ® ) + + +++ ++ ++ ++ ++ ± ± Risperidone (Risperdal ® ) + + + + + ++ + +++ +++ Ziprasidone (Geodon ® ) +++ ± ± ± ± ± ± + ±

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