AMDA Pocket Guidelines

Dementia Depression Delirium

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25 STEP 16: Manage any BPSD 15 ➤ Prior to instituting any treatments, rule out reversible causes and try non-pharmacological management strategies first. Refer to Appendix C. ➤ Document target symptom. Clearly document treatment targets, i.e. what symptoms are we treating and what monitoring strategy will be used to determine effectiveness. ➤ Always justify use of an antipsychotic. The treatment target symptom must present a danger to the person or other persons according to CMS guidelines for the use of an antipsychotic in nursing homes. Refer to Appendix G. • Appropriate antipsychotic treatment targets ▶ Aggressive behavior causing physical harm to self or others ▶ Hallucinations causing distress to the patient ▶ Delusions distressing to patient or other residents ▶ Agitation causing severe distress to patient • Inappropriate antipsychotic treatment target symptoms ➤ Evidence supports modest symptom improvement with aripiprazole, haloperidol, olanzapine, quetiapine, and risperidone. Refer to Appendix A. ➤ Special populations • Frontotemporal dementia, some evidence for trazodone or selective serotonin reuptake inhibitors (SSRIs). • Parkinson's disease and Lewy body dementia, quetiapine or clozapine are preferred due to lower incidence of extrapyramidal symptoms. • Renal impairment, reduced dose of risperidone. Titrate slowly. • Hepatic impairment, reduced dose of olanzapine. ▶ Wandering ▶ Insomnia ▶ Poor self-care ▶ Restlessness ▶ Nervousness ▶ Fidgeting ▶ Mild anxiety ▶ Impaired memory ▶ Uncooperativeness without aggressive behavior ▶ Inattention or indifference to surroundings ▶ Sadness or crying alone that is not related to depression or another psychiatric disorder

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