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Dyslipidemia-II NLA

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21 Î Increased ASCVD risk is associated with geographic region, genetics, culture (shared values, beliefs, customs, and learned behavior) and the social determinants of health (low income, lack of access to, or inadequate, health insurance, and low educational attainment) for all of which "race" is a crude proxy. • Broad policy areas for addressing racial/ethnic health care disparities include raising public and provider awareness of racial/ethnic disparities in care and outcomes, expanding health insurance coverage, improving capacity and number of providers in underserved communities, and increasing the knowledge base on causes and interventions to reduce disparities. Î The lifespan of patients with HIV infection and suppressed viral replication now approaches that of the general population. This prolonged survival is associated with an increased prevalence of co-morbidities, including CVD, presumably due in part to the inflammation, immune activation, and immune senescence associated with this viral infection. Results from observational studies support an increased CVD risk in the HIV population. However there is a paucity of data linking cardiovascular outcomes with lipid goals and no validated risk stratification schemes for this patient population. Î CVD has been found to be elevated across the spectrum of inflammatory diseases, including temporal arteritis, with perhaps the highest risk among young women with systemic lupus erythematosus. Currently no validated strategy exists in the United States that can integrate the burden of chronic inflammation with traditional risk factors to quantify cardiovascular risk in these patients. This discussion focuses on rheumatoid arthritis because it is the most common inflammatory disease with the most data available on cardiovascular risk. Special Populations

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