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Blood Cholesterol

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22 Diagnosis Table 8. Racial/Ethnic Issues in Evaluation, Risk Decisions, and Treatment of ASCVD Risk Racial/Ethnic Groupings Asian Americans a Hispanic/Latino Americans b Blacks Comments Treatment Lifestyle counseling (use principles of Mediterranean and DASH diets) Use lifestyle counseling to recommend a heart- healthy diet consistent with racial/ethnic preferences to avoid weight gain and address BP and lipids. Use lifestyle counseling to recommend a heart-healthy diet consistent with racial/ethnic preferences to avoid weight gain and address BP and lipids. Use lifestyle counseling to recommend a heart- healthy diet consistent with racial/ ethnic preferences to avoid weight gain and address BP and lipids. Asian and Hispanic/ Latino groups need to be disaggregated because of regional differences in lifestyle preferences. Challenge is to avoid increased sodium, sugar, and calories as groups acculturate. Intensity of statin therapy and response to LDL-C lowering Japanese patients may be sensitive to statin dosing. In an open-label, randomized primary- prevention trial, Japanese participants had a reduction in CVD events with low- intensity doses of pravastatin as compared with placebo. In a secondary- prevention trial, Japanese participants with CAD benefitted from a moderate- intensity dose of pitavastatin. No sensitivity to statin dosage is seen, as compared with non-Hispanic white or black individuals. No sensitivity to statin dosage is seen, as compared with non- Hispanic white individuals. Using a lower statin intensity in Japanese patients may give results similar to those seen with higher intensities in non-Japanese patients.

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