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21 Table 8. Racial/Ethnic Issues in Evaluation, Risk Decisions, and Treatment of ASCVD Risk Racial/Ethnic Groupings Asian Americans a Hispanic/Latino Americans b Blacks Comments Risk Decisions PCE No separate PCE is available; use PCE for whites. PCE may underestimate ASCVD risk in South Asians. PCE may overestimate risk in East Asians. In terms of CAC burden, South Asian men were similar to non-Hispanic white men, but higher CAC when than blacks, Latinos, and Chinese Americans. South Asian women had similar CAC scores to whites and other racial/ ethnic women, although CAC burden higher in older age. No separate PCE is available; use PCE for non- Hispanic whites. If African-American ancestry is also present, then use PCE for blacks. CAC predicts similarly in whites and in those who identify as Hispanic/Latino. Use PCE for blacks. In MESA, CAC score was highest in white and Hispanic men, with blacks having significantly lower prevalence and severity of CAC. Country- specific race/ ethnicity, along with socioeconomic status, may affect estimation of risk by PCE. Risk factor differences in MESA between ethnicities did not fully explain variability in CAC. However, CAC predicted ASCVD events over and above traditional risk factors in all ethnicities.

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