Table 1. Risk Factor-Control During Follow-up
Increased Risk No Increased Risk Point Estimate
a
Confidence
Systolic blood
pressure (SBP)
(out of target)
1.7 High
Mean arterial
pressure (MAP)
(out of target)
2.8 Moderate
Diastolic blood
pressure (DBP)
(out of target)
2.2 Moderate
Strict blood pressure
control plus low
distal flow status
6.2 Low
Total cholesterol
(TC) (out of target)
2.1 Moderate
TC/HDL ratio
(out of target)
1.9 Moderate
Non- high-density
lipoprotein
cholesterol (HDL-C)
(out of target)
1.4 Low
Low-density
lipoprotein
cholesterol (LDL-C)
(out of target)
1.3 Low
Physical activity
(out of target)
6.7 High
Alcohol use
(out of target)
1.8 Moderate
Hemoglobin A1c
(HbA1C)
(out of target)
2.3 Moderate
a
e evidence is insufficient to support or refute that failure to achieve a body mass index
(BMI) target and smoking cessation predicts an increased risk of recurrent stroke.
Predictors of Recurrent Stroke or Death in Patients With s-ICAS Table 2. Modifiable Risk Factors at Baseline
Increased Risk No Increased Risk Point Estimate
a
Confidence
SBP 1.3 Low
DBP (lower) 0.9 Moderate
Hypertension
(no history)
0.9 Low
HDL-C 1.0 Low
Glucose >200 mg/dL 2.0 Moderate
History of diabetes 1.6 Moderate
Elevated triglycerides 1.6 Moderate
Physical activity
(less active)
1.1 Low
BMI 1.4 Low
Smoker 1.0 Low
History of carotid artery
disease
0.95 Low
Failure of
anti-thrombotic therapy
1.0 Low
a
ere is insufficient evidence to support or refute the following modifiable risk factors in
predicting an increased risk of recurrent stroke: baseline HbA1c, baseline TC, a history
of peripheral vascular disease, a history of dyslipidemia, baseline LDL-C, elevated
lipoprotein (a), metabolic syndrome, alcohol use, high-sensitivity C-reactive protein
(hs-CRP), and a positive myocardial single-photon emission computerized tomography
(SPECT) scan.
Treatment
