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Special Populations
Table 21. Safety of Cardiovascular Medications During
Pregnancy and Lactation
Medication Safety in Pregnancy Safety in Lactation
Anticoagulants
Warfarin LD S
Unfractionated heparin S S
Enoxaparin S S
Fondaparinux LD U
Argatroban LD U
Bivalirudin LD U
Antiplatelets
Aspirin (low dose) LD LD
Clopidogrel LD LD
Prasugrel LD U
Ticagrelor LD U
rombolytics
Alteplase LD U
Streptokinase LD U
Hypertension
Labetalol S LD
Nifedipine S S
Alpha-methyldopa (oral) S S
Hydralazine LD S
Nitroglycerin LD U
Nitroprusside LD LD
Isosorbide dinitrate LD U
Amlodipine LD LD
Furosemide S LD
Hydrochlorothiazide LD S
Clonidine LD U
(cont'd)
