57
Table 21. Safety of Cardiovascular Medications During
Pregnancy and Lactation
Medication Safety in Pregnancy Safety in Lactation
Cautionary Use and Contraindicated in Pregnancy
Atenolol C LD
ACE inhibitor class
†
C LD
ARB class C U
Aldosterone antagonists C C
Statin class LD C
DOAC C C
ERAs (eg, bosentan) C C
Color key: C, contraindicated; LD, limited data, use with caution; S, considered safe; and U,
conflicting data, unknown.
* May be used if other therapies fail.
†
Captopril, benazepril, and enalapril are considered safe during lactation.
Adapted with permission from Halpern DG, et al. J Am Coll Cardiol. 2019;73:457-476. Copyright
2019 American College of Cardiolog y Foundation.
(cont'd)
Table 22. The Geriatric 5 Ms
Mind Mentation, dementia, delirium, depression
Mobility Impaired gait and balance, fall injury prevention
Medications Polypharmacy, deprescribing, optimal prescribing
Adverse medication effects and medication burden
Multicomplexity Multimorbidity
Complex biopsychosocial situations
Matters most Each individual's own meaningful health outcome goals and care
preferences
Adapted with permission from Molnar F, et al. Can Fam Physician. 2019;65:39. Copyright 2017
Canadian Geriatrics Society and from Molnar F, et al. Copyright 2019 e College of Family
Physicians of Canada. e GERIATRIC 5Ms, Copyright © 2017 Frank Molnar, Allen Huang,
Mary Tinetti. 2017.
e Geriatric 5Ms may be used for educational purposes with full attribution and no alterations.
is work is bound by the Creative Commons license CC-BY-NC-ND 4.0 (https://
creativecommons.org/licenses/by-nc-nd/4.0/).
6.6. Older Adults
