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Cardiac Physiologic Pacing for the Avoidance and Mitigation of Heart Failure

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10 Indications for CPP in Patients with Indications for Pacemaker Therapy Substantial ventricular pacing COR LOE Recommendations 2a B-R (CRT) 1. In patients with an indication for permanent pacing with an LVEF 36%–50% who are anticipated to require substantial ventricular pacing, CPP is reasonable to reduce the risk of PICM. B-NR (HBP, LBBAP) 2b B-NR 2. In patients with normal LVEF who are anticipated to require substantial ventricular pacing, it may be reasonable to treat patients with CPP to reduce the risk of PICM. 2b C-LD 3. In patients who are ventricular pacing-dependent undergoing HBP pacemaker implantation, placement of an additional backup lead may be reasonable to mitigate the risk of high pacing capture thresholds, lead dislodgment, loss of capture, or oversensing. Less than substantial ventricular pacing COR LOE Recommendations 2a B-R 1. In patients with an indication for permanent pacing with LVEF >35% who are anticipated to require less than substantial ventricular pacing, it is reasonable to choose traditional RV lead placement and minimize RVP. 2b C-LD 2. In patients with an indication for permanent pacing with LVEF 36%–50% who are anticipated to require less than substantial ventricular pacing, a CSP lead with HBP or LBBAP may be considered as an alternative to an RVP lead. 2b C-LD 3. In patients with an indication for permanent pacing, LVEF 36%–50% and LBBB, and who are anticipated to require less than substantial ventricular pacing, CPP may be considered to potentially improve symptoms and LVEF. 2b C-LD 4. In patients who are undergoing permanent pacing with normal LVEF and are anticipated to require less than substantial ventricular pacing, an LBBAP lead may be considered as an alternative to an RVP lead. 3: No Benefit B-R 5. In patients with normal LVEF who are anticipated to require less than substantial ventricular pacing, CRT with BiV pacing is not indicated.

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