AAN GUIDELINES Bundle

106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2021 All rights reserved AANPDN11213 Disclaimer is pocket guide attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. is pocket guide should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Abbreviations AAN, American Academy of Neurolog y; CBT, cognitive behavioral therapy; CDC, Centers for Disease Control and Prevention; SNRI, serotonin-norepinephrine reuptake inhibitor; TCA, tricyclic antidepressants Source Price R, Smith D, Franklin G, et al. Oral and topical treatment of painful diabetic polyneuropathy: practice guideline update summary. Neurolog y. 2021;98(1):1-13. Classification of Management Recommendations Classification Definition Level (A) Denotes a practice recommendation that must be done. In almost all circumstances, adherence to the recommendation will improve health- related outcomes. Almost all patients in this circumstance would desire that the recommendation be followed. Level (B) Indicates a recommendation that should be done. In most circumstances, adherence to the recommendation will likely improve health-related outcomes. Most patients in this circumstance would want the recommendation to be followed. Level (C) Represents a recommendation that may be done. In some circumstances, adherence to the recommendation might improve health-related outcomes. Level (U) Indicates that the available evidence is insufficient to support or refute the efficacy of an intervention. Level (R) Assigned when the balance of benefits and harms is unknown and the intervention is known to be exorbitantly expensive or have important risks. is level designates that the intervention should not be used outside of a research setting.

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