ASCO GUIDELINES Bundle

Treatment of Early-Stage Colorectal Cancer

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3 Treatment Table 2. Non-metastatic, non-obstructing colon cancer Colon Cancer Stage I: T1-2N0M0, Colon Cancer Stage IIA: T3N0 (no high-risk features), Colon Cancer Stage IIA: T3N0 (with high risk features) Population Intervention Setting Patients with non-obstructing, resectable, localized colon cancer General surgeons should perform open resection following standard oncologic principles. (Strong Recommendation; H) Basic and Limited Patients with non-obstructing, resectable, localized colon cancer If suitable, surgical oncologists and/or colorectal surgeons with adequate training in laparoscopic or minimally invasive techniques should perform laparoscopic or minimally invasive resection following standard oncologic principles and, if Maximal, using the most appropriate techniques and instruments. (Strong Recommendation; H) Enhanced and Maximal Patients with non-obstructing, resectable, localized colon cancer If laparoscopy is contraindicated, surgical oncologists and/or colorectal surgeons should use an open surgical approach. (Strong Recommendation; H) Enhanced and Maximal Table 3. Colon Cancer Stages IIB-IIC: T4N0 (Non-obstructing) Population Intervention Setting Patients with non- obstructing, locally advanced (ie., with invasion of adjacent structures) colon cancer General surgeons should perform an open en bloc resection (including adjacent invaded organ) following standard oncologic principles. (Strong Recommendation; H) Basic Patients with non-obstructing, locally advanced (ie., with invasion of adjacent structures) colon cancer with contraindications and/or en bloc resection not possible If contraindications and/or en bloc resection not possible, efforts should be made to transfer a patient to a higher-level facility. (Strong Recommendation; IC-H) Basic and Limited

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