14
Disclaimer
is pocket guide is derived om recommendations in the American Society of Clinical
Oncology Guideline. is resource is a practice tool based on ASCO
®
practice guidelines and is
not intended to substitute for the independent professional judgment of the treating physician.
Practice guidelines do not account for individual variation among patients. is pocket guide
does not purport to suggest any particular course of medical treatment. Use of the practice
guidelines and this resource are voluntary. e practice guidelines and additional information
are available at www.asco.org/resource-stratified-guidelines. Copyright © 2019 by American
Society of Clinical Oncology. All rights reserved.
Source
Costas-Chavarri A, Nandakumar G, Temin S, Lopes G, Cervantes A, Cruz Correa M,
Engineer R, Hamashima C, Ho GF, Huitzil FD, Malekzadeh Moghani M, Sharara A, Stern
MC, Teh C, Vázquez Manjarrez SE, Verjee A, Yantiss R, Shah M. Treatment of Patients with
Early-Stage Colorectal Cancer: ASCO Resource-Stratified Guideline. J Global Oncol. 2019
Feb 25; doi: 10.1200/JGO.18.00214
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Copyright © 2019 All rights reserved
ASCOCRCTx1923
ASCO believes that cancer clinical trials are vital to inform medical decisions and
improve cancer care and that all patients should have the opportunity to participate.
Additional information, which may include data supplements, slide sets, and other clinical
tools and resources, is available at www.asco.org/resource-stratified-guidelines
Abbreviations
CEA, carcinoembryonic antigen testing ; CRC, colorectal cancer; CRM, circumferential
resection margin; CRT, chemoradiation therapy; CT, computed tomography; CXR,
chest x-ray; DRE, digital rectal exam; EMVI, extramural vascular invasion; MRI, magnetic
resonance imaging ; SCPRT, short course-preoperative radiotherapy; TEM, transanal
endoscopic microsurgery; TEM, transanal endomucosal microsurgery; TME, total
mesorectal excision; q, every
Recommendation Grading
Type Benefit/harm Evidence Quality
Strength of
Recommendation
EB Evidence-
based
B Benefits
outweigh harms
H High Strong
CB
Consensus-
based
H Harms outweigh
benefits
I Intermediate Moderate
IC Informal
consensus
B/H Relative balance
of benefits and
harms
L Low Weak
Ins Insufficient
