ASCO GUIDELINES Bundle

Treatment of Early-Stage Colorectal Cancer

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7 Table 7. Rectal Cancer Stage I– clinical stage T2 N0 Population Intervention Setting Patients with nonmetastatic cT2N0 rectal cancer General surgeons should perform surgery following TME principles. (Strong Recommendation; H) Basic and Limited Patients with nonmetastatic cT2N0 rectal cancer Surgical oncologists and/or colorectal surgeons should perform TME following standard oncologic principles. (Strong Recommendation; H) Enhanced Patients with nonmetastatic cT2N0 rectal cancer Surgical oncologists and/or colorectal surgeons should perform TME following standard oncologic principles, using the most advanced techniques. (Strong Recommendation; H) Maximal Table 8. Rectal Cancer Stage IIA– clinical stage T3 N0 Population Intervention Setting Patients with clinically resectable cT3N0 rectal cancer If TME is feasible, general surgeons should perform surgery following TME principles. (Moderate Recommendation; I) Basic and Limited Patients with clinically resectable cT3N0 rectal cancer If surgery following TME principles is not feasible, then clinicians should transfer patients to a higher capacity facility. (Moderate Recommendation; IC-I) Basic and Limited Patients with clinically resectable cT3N0 rectal cancer at high risk who did not receive neoadjuvant treatment Surgeons or oncologists may offer basic adjuvant therapy; limited chemotherapy may be offered. (Moderate Recommendation; I) Basic Patients with clinically resectable cT3N0 rectal cancer at high risk who did not receive neoadjuvant treatment Surgeons or oncologists may offer basic adjuvant chemotherapy; radiation therapy may be offered in addition to chemotherapy, if available. (Moderate Recommendation; I) Limited Patients with clinically resectable cT3N0 rectal cancer where there is no indication on MRI that surgery is likely to be associated with either an R2 or an R1 resection Surgical oncologists and/or colorectal surgeons should perform TME following standard oncologic principles and, in Maximal settings, using the most advanced techniques. (Strong Recommendation; H) Enhanced and Maximal

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