Table 3. The Talcott's Classification
Group I Inpatients (at the time of fever onset)
Group II Outpatients with acute comorbidity requiring by itself hospitalization
Group III Outpatients without comorbidity but with uncontrolled cancer
Group IV
a
Outpatients with cancer controlled and without comorbidity
a
Group IV is considered to be low risk.
Table 4. The Clinical Index of Stable Febrile Neutropenia
(CISNE) Includes Six Explanatory Variable Associated
with Serious Complications
a
Explanatory variable
Number of
points
Eastern Cooperative Oncolog y Group performance status ≥2 2
Chronic obstructive pulmonary disease 1
Chronic cardiovascular disease 1
National Cancer Institute Common Toxicity Criteria mucositis of
grade ≥2
1
Monocytes <200 per µL 1
Stress-induced hyperglycemia 2
a
ese factors are integrated into a score ranging from 0–8, which classifies patients into three prognostic
classes: low risk (0 points), intermediate risk (1–2 points), and high risk (≥3 points).
