ASCO GUIDELINES Bundle

Metastatic Carcinoma and Myeloma of the Femur

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Strength of Recommendations Strength Strength Visual Definition Strong ★★★★ Evidence from two or more "High" quality studies with consistent findings for recommending for or against the intervention. Also requires no reasons to downgrade from the EtD framework. Moderate ★★★★ Evidence from two or more "Moderate" quality studies with consistent findings recommending for or against the intervention, prognostic factor, or diagnostic test, or evidence from a single "High" quality study for recommending for or against the intervention. Limited ★★★★ Evidence from two or more "Low" quality studies with consistent findings or evidence from a single "Moderate" quality study recommending for or against the intervention, or diagnostic or the evidence is insufficient or conflicting and does not allow a recommendation for or against the intervention. Consensus ★★★★ In the absence of reliable evidence, the clinical practice guideline development group is making a recommendation based on their clinical opinion.

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