ASCO GUIDELINES Bundle

Colorectal Cancer Early Detection

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Table 5. People With Positive Pre-Malignant Polyps or Other Abnormal Screening Results Basic/ Limited Enhanced Maximal 3.9 Evaluation of morpholog y (Strong Recommendation; Ins) N/A Endoscopic assessment of lesion using enhanced endoscopy methods (if available may include chromoendoscopy); clinicians should follow the BSG guideline. 3.10 Mucosal tattooing (Weak Recommendation; Ins) N/A If lesion cannot be removed (in BSG guidelines); if large lesion has a high likelihood of malignancy should be performed. For patients with polyps that are completely removed, clinicians may perform tattooing for surveillance purposes. 3.11 Histolog y/ patholog y (Strong Recommendation; Ins) N/A Removed lesions should be retrieved for histologic exam; confirm negative borders of resection. 3.12 Referral to surgery (Strong Recommendation; Ins) N/A Only patients with lesions that cannot be removed endoscopically should be referred to surgery. 1 BSG = British Society of Gastroenterolog y/Association of Coloproctologists of Great Britain and Ireland guidelines for the management of large non-pedunculated colorectal polyps. Source: Rutter MD, et al. Gut 2015;0:1–27. doi:10.1136/gutjnl-2015-309576 Availabe at: https://www.bsg.org.uk/asset/14074495-3BF4-4EA8-BED8E740BA1E6177 Table 6. Optimal Strategy For Workup/Diagnosis for Those With Symptoms Basic Limited Enhanced Maximal 4.1 DRE (IC-Ins) DRE may be performed (standard part of physical). N/A physical exam 4.2 Double contrast barium enema (IC-Ins) Double contrast barium enema may be performed. N/A 4.3 For those without contraindications to colonoscopy Colonoscopy with biopsy for those without contraindications should be performed, if colonoscopy is available, including by referral. Colonoscopy with biopsy for those without contraindications should be performed. (cont'd) Treatment

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