Treatment
Summary of Recommendations
Interventions
Strength of
recommendation
Strength of
the evidence Benefits Harms
a
Prevention
Acetylcysteine Moderate against Intermediate Low Low
Acetyl-L-
Carnitine
Strong against High No evidence of
efficacy
High
Acupuncture No recommendation Low Low Moderate
Amifostine Moderate against Intermediate Low Moderate
Amitriptyline Moderate against Intermediate No evidence of
efficacy
Moderate
Calcium &
magnesium
Moderate against Intermediate Low Low
Cannabinoids Moderate against Intermediate Low Low
Calmangafodipir Moderate against Intermediate Low Low
Carbamazepine/
Oxcarbazepine
Moderate against Intermediate Low Low
L-carnosine Moderate against Intermediate Low Low
Compression
erapy
No recommendation Low Low Low
Cryotherapy No recommendation Low Low Moderate
Diethyldithio-
carbamate
(DDTC)
Moderate against Intermediate No evidence of
efficacy
High
Exercise No recommendation Low Low Low
Gabapentin/
pregabalin
Moderate against Intermediate Low Low
Ganglioside-
monosialic acid
(GM-1)
No recommendation Low Low Low
Glutamate/
Glutamine
Moderate against Intermediate Low Low
Glutathione
(GSH)
Moderate against Intermediate Low Low
