Recommendation 1.4
➤ Clinicians should NOT offer the following agents for the prevention of
CIPN to cancer patients undergoing treatment with neurotoxic agents:
• All-trans retinoic acid
• Amifostine
• Amitriptyline
• Calcium magnesium
• Calmangafodipir
• Cannabinoids
• Carbamazepine
• L-carnosine
• Diethyldithio-carbamate (DDTC)
• Gabapentin/pregabalin
• Glutamate
• Glutathione (GSH) for patients receiving paclitaxel/carboplatin chemotherapy
• Goshajinkigan (GJG)
• Metformin
• Minocycline
• N-acetylcysteine
• Nimodipine
• Omega-3 fatty acids
• Org 2766
• Oxcarbazepine
• rhuLIF
• Venlafaxine
• Vitamin B
• Vitamin E
(Moderate recommendation; EB-NB-I)
