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Treatment
Antiplatelet Therapy in Patients After CABG
COR LOE
Recommendations
1 A 1. In patients undergoing CABG, aspirin (100–325 mg daily)
should be initiated within 6 hours postoperatively and then
continued indefinitely to reduce the occurrence of SVG
closure and adverse cardiovascular events.
2b B-R 2. In selected patients undergoing CABG, DAPT with aspirin
and ticagrelor or clopidogrel for 1 year may be reasonable to
improve vein graft patency compared with aspirin alone.
Beta Blockers in Patients After Revascularization
COR LOE
Recommendation
3: No
benefit
C-LD 1. In patients with SIHD and normal left ventricular function,
the routine use of chronic oral beta blockers is NOT
beneficial to reduce cardiovascular events after complete
revascularization.
Beta Blockers for the Prevention of Atrial Fibrillation After
CABG
COR LOE
Recommendation
1 B-R 1. In patients after CABG, beta blockers are recommended and
should be started as soon as possible to reduce the incidence
or clinical sequelae of postoperative atrial fibrillation.
Antiplatelet Therapy in Patients With Atrial Fibrillation on
Anticoagulation After PCI
COR LOE
Recommendations
1 B-R 1. In patients with atrial fibrillation who are undergoing PCI
and are taking oral anticoagulant therapy, it is recommended
to discontinue aspirin treatment after 1 to 4 weeks while
maintaining P2Y12 inhibitors in addition to a non-vitamin
K oral anticoagulant (rivaroxaban, dabigatran, apixaban, or
edoxaban) or warfarin to reduce the risk of bleeding.
2a B-R 2. In patients with atrial fibrillation who are undergoing PCI, are
taking oral anticoagulant therapy, and are treated with DAPT
or a P2Y12 inhibitor monotherapy, it is reasonable to choose a
non-vitamin K oral anticoagulant over warfarin to reduce the
risk of bleeding.
