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2021 Chest Pain Guidelines

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41 5.1.2. Low-Risk Patients With Stable Chest Pain and No Known CAD COR LOE Recommendations 1 B-NR 1. For patients with stable chest pain and no known CAD presenting to the outpatient clinic, a model to estimate pretest probability of obstructive CAD is effective to identify patients at low risk for obstructive CAD and favorable prognosis in whom additional diagnostic testing can be deferred. 2a B-R 2. For patients with stable chest pain and no known CAD categorized as low risk, CAC testing is reasonable as a first- line test for excluding calcified plaque and identifying patients with a low likelihood of obstructive CAD. 2a B-NR 3. For patients with stable chest pain and no known CAD categorized as low risk, exercise testing without imaging is reasonable as a first-line test for excluding myocardial ischemia and determining functional capacity in patients with an interpretable ECG.

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