40
Treatment
Pretest Probabilities of Obstructive CAD in Symptomatic Patients
(A) according to age, sex, and symptoms;
(B) according to age, sex, symptoms, and CAC
Age, y Chest Pain Dyspnea
Men Women Men Women
30–39 ≤4 ≤5 0 3
40–49 ≤22 ≤10 12 3
50–59 ≤32 ≤13 20 9
60–69 ≤44 ≤16 27 14
70+ ≤52 ≤27 32 12
Intermediate–High
>15%
Low
≤15%
>15%–50% ≤15% >50%
Pretest probability based on age,
sex, and symptoms
A
Pretest probability based on age,
sex, symptoms, and CAC score
+
B
CAC
1–99
CAC
≥100–999
CAC
≥1,000
e Pretest Probability shown is for patients with anginal symptoms. Patients with lower risk
symptoms would be expected to have lower PTP.
e darker green and orange shaded regions denote the groups in which non-invasive testing is
most beneficial (pre-test probability >15%). e light green shaded regions denote the groups
with pre-test probability of CAD ≤15% in which the testing for diagnosis may be considered
based on clinical judgement.
If CAC available, can use to estimate pretest probability based on CAC Score.
Adapted and modified from Juarez-Orozc ESC 2019 Nov 1;20(11):1198-1207.
+ Winther, S. et al. J Am Coll Cardiol. 2020 Nov 24;76(21):2421-2432.
Figure 11. Pretest Probabilities of Obstructive CAD in
Symptomatic Patients According to Age, Sex, and Symptoms
