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2021 Chest Pain Guidelines

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39 4.3.1. Evaluation of Acute Chest Pain With Suspected Gastrointestinal Syndromes COR LOE Recommendation 2a C-LD 1. In patients with recurrent acute chest pain without evidence of a cardiac or pulmonary cause, evaluation for gastrointestinal causes is reasonable. 4.3.2. Evaluation of Acute Chest Pain With Suspected Anxiety and Other Psychosomatic Considerations COR LOE Recommendation 2a B-R 1. For patients with recurrent, similar presentations for acute chest pain with no evidence of a physiological cause on prior diagnostic evaluation including a negative workup for myocardial ischemia, referral to a cognitive-behavioral therapist is reasonable. 4.3.3. Evaluation of Acute Chest Pain in Patients With Sickle Cell Disease COR LOE Recommendations 1 B-NR 1. In patients with sickle cell disease who report acute chest pain, emergency transfer by EMS to an acute care setting is recommended. 1 C-LD 2. In patients with sickle cell disease who report acute chest pain, ACS should be excluded.

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