Diabetes Mellitus (AACE)

Recommendation Grading Quality of Evidence Evidence Level 1 = strong 2 = intermediate 3 = weak 4 = no evidence Recommendation Grade A = strong B = intermediate C = weak D = not evidence based For a full description of the AACE Evidence Rating System please see the full guidelines. Abbreviations ac, before meals; AACE/ACE, American Association of Clinical Endocrinologists/ American College of Endocrinology; ACE, angiotensin-converting enzyme; ARB, angiotensin II receptor blocker; bid, twice daily; CDE, certified diabetes educator; CHF, congestive heart failure; Clcr, creatinine clearance; CSII, continuous subcutaneous insulin infusion; CV, cardiovascular; CVD, cardiovascular disease; dL, deciliter; DM, diabetes mellitus; DPP-4 inhibitor, dipeptidyl-peptidase 4 inhibitor; FDA, US Food and Drug Administration; FPG, fasting plasma glucose; g, gram; GDM, gestational diabetes mellitus; GFR, glomerular filtration rate; GI, gastrointestinal; GIP, glucose dependent insulinotropic polypeptide; GLP-1, glucagonlike peptide 1; h, hour; HbA1c, hemoglobin HbA1c; HDL-C, high-density lipoprotein cholesterol; H&P, history and physical; HRV, heart rate variability; IV, intravenous; IV Ig, intravenous immunoglobulin; kg, kilogram; lb, pound; LDL-C, low-density lipoprotein cholesterol; m, meter; max, maximum; mcg, microgram; MDI, multiple daily injections; mg, milligram; MIBG, metaiodobenzylguanidine; min, minute; mL, milliliter; MUGA, multigated radionuclide angiogram; NPH, neutral protamine Hagedorn; NYHA, New York Heart Association cardiac disease and functional capacity; OGTT, oral glucose tolerance test; PG, plasma glucose; PPG, postprandial glucose; Rx, prescription; SMBG, self-monitoring of blood glucose; SU, sulfonylurea; tid, three times daily; T1DM, type 1 diabetes mellitus; T2DM, type 2 diabetes mellitus; TZD, thiazolidinedione; U, unit Source Handelsman Y, Mechanick JI, Blonde L, Grunberger G. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for developing a diabetes mellitus comprehensive care plan. Endocr Pract. 2011;17(Suppl 2):1-53. Rodbard HW, Jellinger PS, Davidson JA, et al. Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on type 2 diabetes mellitus: An algorithm for glycemic control. Endocr Pract. 2009;15:540-559. [Erratum in Endocr Pract. 2009;15:768-770] Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician after consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. DIA081125 5740 Executive Drive  Suite 218 Baltimore, MD 21228  TEL: 410-869-3332  •  FAX: 410-744-2150  For additional copies: orders@GuidelineCentral.com Copyright © 2011 All rights reserved

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