Treatment
Drugs Used for Acromegaly
Drug
(Brand) How Supplied Dosing
Cabergoline
a
(Dostinex
®
)
• Scored 0.5 mg tablets • 0.5-2.0 mg PO weekly,
usually split twice a week
Lanreotide
b
(Somatuline
®
Depot)
• 60, 90, and 120 mg sterile,
single-use, pre-filled
syringes
• 60-120 mg deep subcut
q4wks
Octreotide
b
(Sandostatin
®
)
• 50, 100 & 500 mcg/mL
ampules
• 50-500 mcg subcut tid
(Sandostatin
®
LAR)
• 10, 20 & 30 mg/6 mL vials • 10-40 mg intraglutelly
q4wks (monthly)
Pegvisomant
b
(Somavert
®
)
• 10, 15, 20, 25 & 30 mg
powder for reconstitution
• 40 mg subcut, then
10-30 mg daily based on
serum IGF-1
a
FDA-approved for hyperprolactinemic disorders
b
FDA-approved for acromegaly
