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Copyright © 2018 All rights reserved
ASCOFEV1833
Disclaimer
is pocket guide is derived om recommendations in the American Society of Clinical Oncolog y
Guideline. is resource is a practice tool based on ASCO
®
practice guidelines and is not intended
to substitute for the independent professional judgment of the treating physician. Practice guidelines
do not account for individual variation among patients. is pocket guide does not purport to
suggest any particular course of medical treatment. Use of the practice guidelines and this resource
are voluntary. e practice guidelines and additional information are available at www.asco.org/
supportive-care-guidelines. Copyright © 2018 by American Society of Clinical Oncolog y.
All rights reserved.
Source
Taplitz RA et al. Outpatient Management of Fever and Neutropenia in Adults Treated for
Malignancy: American Society of Clinical Oncolog y and Infectious Diseases Society of America
Clinical Practice Guideline Update. J Clin Oncol. 2018 Feb 20; doi: 10.1200/JCO.2017.77.6211.
[Epub ahead of print]
ASCO believes that cancer clinical trials are vital to inform medical decisions and
improve cancer care and that all patients should have the opportunity to participate.
Additional information, which may include data supplements, slide sets,
frequently asked questions, and other clinical tools and resources, is available at
www.asco.org/supportive-care-guidelines
Recommendation Grading
Type Evidence Quality
Strength of
Recommendation
EB Evidence-based H High Strong
I Intermediate Moderate
IC
Informal Consensus L Low Weak
Ins Insufficient
Abbreviations
ANC, absolute neutrophil count; CISNE, Clinical Index of Stable Febrile Neutropenia;
CNS, central nervous system; CSF, cerebrospinal fluid; ED, emergency department; ESBL,
extended-spectrum β-lactamase; FN, febrile neutropenia; Hb, hemoglobin; Hct, hematocrit;
HSCT, hematopoietic stem cell transplantation; IV, intravenous; KPC, Klebsiella pneumoniae
carbapenemase-producing bacteria; MASCC, Multinational Association for Supportive Care in
Cancer; MRSA, methicillin-resistant Staphylococcus aureus; ULN, upper limit of normal; VRE,
vancomycin-resistant enterococcus
