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Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy

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106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2018 All rights reserved ASCOFEV1833 Disclaimer is pocket guide is derived om recommendations in the American Society of Clinical Oncolog y Guideline. is resource is a practice tool based on ASCO ® practice guidelines and is not intended to substitute for the independent professional judgment of the treating physician. Practice guidelines do not account for individual variation among patients. is pocket guide does not purport to suggest any particular course of medical treatment. Use of the practice guidelines and this resource are voluntary. e practice guidelines and additional information are available at www.asco.org/ supportive-care-guidelines. Copyright © 2018 by American Society of Clinical Oncolog y. All rights reserved. Source Taplitz RA et al. Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncolog y and Infectious Diseases Society of America Clinical Practice Guideline Update. J Clin Oncol. 2018 Feb 20; doi: 10.1200/JCO.2017.77.6211. [Epub ahead of print] ASCO believes that cancer clinical trials are vital to inform medical decisions and improve cancer care and that all patients should have the opportunity to participate. Additional information, which may include data supplements, slide sets, frequently asked questions, and other clinical tools and resources, is available at www.asco.org/supportive-care-guidelines Recommendation Grading Type Evidence Quality Strength of Recommendation EB Evidence-based H High Strong I Intermediate Moderate IC Informal Consensus L Low Weak Ins Insufficient Abbreviations ANC, absolute neutrophil count; CISNE, Clinical Index of Stable Febrile Neutropenia; CNS, central nervous system; CSF, cerebrospinal fluid; ED, emergency department; ESBL, extended-spectrum β-lactamase; FN, febrile neutropenia; Hb, hemoglobin; Hct, hematocrit; HSCT, hematopoietic stem cell transplantation; IV, intravenous; KPC, Klebsiella pneumoniae carbapenemase-producing bacteria; MASCC, Multinational Association for Supportive Care in Cancer; MRSA, methicillin-resistant Staphylococcus aureus; ULN, upper limit of normal; VRE, vancomycin-resistant enterococcus

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