Disclaimer
is Guideline attempts to define principles of practice that should produce high-quality patient care.
It is applicable to specialists, primary care, and providers at all levels. is Guideline should not be
considered exclusive of other methods of care reasonably directed at obtaining the same results. e
ultimate judgment concerning the propriety of any course of conduct must be made by the clinician
aer consideration of each individual patient situation.
Neither IGC, the medical associations, nor the authors endorse any product or service associated with
the distributor of this clinical reference tool.
Abbreviations
CA, community-associated; CDAD, Clostridium difficile–associated diarrhea; CO-HCFA,
community-onset healthcare facility-associated; FMT, fecal microbiota transplantation;
HO-CDAD, healthcare facility-onset C. difficile associated diarrhea; IV, intravenous;
PO, by mouth; PPI, proton pump inhibitors; RCT, randomized clinical trial
e guidelines provide evidence-based recommendations that have been developed using
GR ADE (Grading of Recommendations, Assessment, Development, and Evaluation)
methodolog y. GR ADE involves structured literature review, systematic reviews and meta-
analyses of combined data, and expert discussion to assess the certainty in the evidence and
determine the strength of each recommendation.
Source
McDoland LC, Gerding DN, Johnson S et al. Clinical Practice Guidelines for Clostridium
difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society
of America (IDSA) and Society for Healthcare Epidemiolog y of America (SHEA). Clinical
Infectious Diseases, cix1085, https://doi.org/10.1093/cid/cix1085
e guidelines were endorsed by the American Society for Health Systems Pharmacists (ASHP),
the Society of Infectious Diseases Pharmacists (SIDP), and the Pediatric Infectious Diseases
Society (PIDS)
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