IDSA/SHEA Clostridium difficile Infection - Merck Flipbook

Clostridium Difficile - Treatment in Adults

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Disclaimer is Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. is Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Abbreviations CA, community-associated; CDAD, Clostridium difficile–associated diarrhea; CO-HCFA, community-onset healthcare facility-associated; FMT, fecal microbiota transplantation; HO-CDAD, healthcare facility-onset C. difficile associated diarrhea; IV, intravenous; PO, by mouth; PPI, proton pump inhibitors; RCT, randomized clinical trial e guidelines provide evidence-based recommendations that have been developed using GR ADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodolog y. GR ADE involves structured literature review, systematic reviews and meta- analyses of combined data, and expert discussion to assess the certainty in the evidence and determine the strength of each recommendation. Source McDoland LC, Gerding DN, Johnson S et al. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiolog y of America (SHEA). Clinical Infectious Diseases, cix1085, https://doi.org/10.1093/cid/cix1085 e guidelines were endorsed by the American Society for Health Systems Pharmacists (ASHP), the Society of Infectious Diseases Pharmacists (SIDP), and the Pediatric Infectious Diseases Society (PIDS) 106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at GuidelineCentral.com Copyright © 2018 All rights reserved IDSACDIF1813f_mer AINF-1231128-0000 02/18 Before prescribing DIFICID®, please read the accompanying Prescribing Informa on. For addi onal copies of the Prescribing Informa on, please call 800-672-6372, visit DIFICID.com, or contact your Merck representa ve.

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