Table 1. Agents Recommended for Deep Vein Thrombosisa Agent (Brand)
Warfarin (Coumadin®, Jantoven® )
Heparins Dalteparin (LMWH) (Fragmin® Enoxaparin (LMWH) (Clexane® Heparin (UFH)
Thrombin IIa Inhibitor Dabigatranc
(Pradaxa®
Factor Xa Inhibitors Apixaband (Eliquis®
)
Fondaparinux (Arixtra® Rivaroxaban (Xarelto®
)
a See Prescribing Information for details. b Adjust to international normalized ratio. c Not FDA-approved for VTE prevention
) ) ) )
Dose POb
Prophylaxis: 5,000 units subcut daily
40 mg subcut daily or 30 mg subcut twice daily 5,000 units subcut q8h
ClCr ClCr
> 30 mL/min: 220 mg PO daily 15-30 mL/min: 150 mg PO daily
2.5 mg PO bid
Prophylaxis: 2.5 mg subcut daily Prophylaxis: 10 mg PO daily
d Apixaban was not FDA approved in the United States at the time of the guideline publication.
