Treatment Figure 1. Prevention of VTE – Orthopedics THA TKA HFS
LMWH ≥ 12 h pre- or post-op (preferred)
LDUH, adjusted-dose VKA, or aspirin
fondaparinux, apixabana dabigatranb
OR IPCD OR , rivaroxaban, ,
Add IPCD in-hospital
LMWH ≥ 12 h pre- or post-op (preferred)
LDUH, fondaparinux, adjusted-dose VKA, or aspirin
OR IPCD OR
Minimum 10-14 days; consider ≤ 35 days
Minimum 10-14 days; consider ≤ 35 days
IPCD only or no prophylaxis Increased bleeding risk
(if unavailable: rivaroxaban or adjusted-dose VKA)
No injections or IPCD Apixabana
or dabigatranb
a Apixaban was not FDA approved in the United States at the time of the guideline publication. b Not FDA-approved for VTE prevention.
