n by Level of Supporting Evidence and Direction of Interaction CNS Drugs
GI Drugs and Food
Alcohol (if concomitant liver disease)
Citalopram Entacapone Sertraline
Cimetidine Fish oil Mango Omeprazole
Boldo-fenugreek Quilinggao
Herbal Supplements Other Drugs
Anabolic steroids Zileuton
Disulfiram Chloral hydrate Fluvoxamine Phenytoin (biphasic with later inhibition)
Felbamate
Grapefruit
Danshen Don quai Lycium barbarum L
PC-SPES Orlistat
Danshen/methyl salicylates
Fluorouracil Gemcitabine Levamisole/ fluorouracil
Paclitaxel Tamoxifen Tolterodine
Acarbose Cyclophosphamide/ methotrexate/ fluorouracil
Daptomycin Danazol Iphosphamide Trastuzumab
Fluoxetine/diazepam Quetiapine
Barbiturates Carbamazepine
Chlordiazepoxide
High vitamin K content foods/ enteral feeds
Soy milk Sucralfate
Etoposide/carboplatin Levonorgestrel
Mercaptopurine
Avocado (large amounts)
Ginseng
Chelation therapy Influenza vaccine Multivitamin supplement
Raloxifene HCL Continued on next page.
