Initial Assessment Adverse Food Reaction (food allergy and celiac disease) Immune Mediated
IgE Mediated (eg, acute
allergy syndrome) urticaria, oral
induced enteropathy, celiac disease)
Non-IgE Mediated (eg, food protein-
Non-IgE Mediated (eg, eosinophilic gastroenteritis )
Mixed IgE and
(eg, allergic contact dermatitis)
Cell Mediated (primarily food intolerances) Not Immune Mediated
Metabolic (eg, lactose intolerance)
Pharmacologic (eg, caffeine)
(eg, scombroid fish toxin)
Toxic
Other/Idiopathic/ Undefined (eg, sulfites)
The Severity of Subsequent Reactions to Peanuts 83 Patients with Peanut Allergy
61 with initial non-LTRs
43 had subsequent reactions 24 non-LTRs LTR, life-threatening reaction 3 19 LTRs initial LTRs 22 with 17 had subsequent reactions 5 non-LTRs 12 LTRs