Pediatric Dose
(Adult/Child) Class
15 mg/kg/dose IV q6h B-II B-II
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
No data C-III/ND
15 mg/kg/dose IV q6h B-II B-II
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
No data
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
No data C-III/ND
15 mg/kg/dose IV q6h B-II B-II
C-III/ND
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to vancomycin‡§
for adult patients (B-III). For children ≥ 12 years, linezolid 600 mg bid.
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to vancomycin‡§
for adult patients (B-III). For children ≥ 12 years, linezolid 600 mg bid.
Comments
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to vancomycin‡§
for adult patients (B-III). For children ≥ 12 years, linezolid 600 mg bid.
15 mg/kg/dose IV q6h B-II/A-II
6-10 mg/kg/day IV daily
10 mg/kg/dose PO/IV q8h Max: 600 mg/dose
If stable: 10-13 mg/kg/dose
No data
PO/IV q6-8h Max: 40 mg/kg/day
B-II/ND B-II/C-III B-II/C-III B-III/A-II
Some experts recommend the addition of rifampin 600 mg daily or 300-450 mg bid to the chosen antibiotic (B-III). For patients with concurrent bacteremia, rifampin should be added aſter clearance of bacteremia.
For children ≥ 12 years, linezolid 600 mg PO/IV bid should be used. A single-strength and double-strength tablet of TMP-SMX‡
TMP, respectively. For an 80 kg adult, 2 DS tablets achieves a dose of 4 mg/kg.
contains 80 mg and 160 mg of
Magnetic resonance imaging (MRI) with gadolinium is the imaging modality of choice, particularly for detection of early osteomyelitis and associated soſt tissue disease (A-II).
Erythrocyte sedimentation rate (ESR) and/or C-reactive protein (CRP) may be helpful to guide response to therapy (B-III).
§ Max: 2 gm/dose. In seriously ill patients consider a loading dose of 25-30 mg/kg (C-III). 9
