ASCO GUIDELINES Bundle

Antiemetics (CINV)

ASCO GUIDELINES App Bundle brought to you fcourtesy of Guideline Central. All of these titles are available for purchase on our website, GuidelineCentral.com. Enjoy!

Issue link: https://eguideline.guidelinecentral.com/i/856867

Contents of this Issue

Navigation

Page 12 of 17

13 Moderate: Upper abdomen, b craniospinal irradiation 5-HT 3 receptor antagonist c Ondansetron 8 mg oral or 8 mg oral dissolving tablet, or 8 mg oral soluble film or 8 mg or 0.15 mg/kg IV Use as prophylactic therapy. Once daily to twice daily on days of radiation therapy, with first dose given before radiation therapy. d Granisetron 2 mg oral or 1 mg or 0.01 mg/kg IV Use as prophylactic therapy. Once daily on days of radiation therapy, before radiation therapy. d Tropisetron 5 mg oral or IV Use as prophylactic therapy. Once daily on days of radiation therapy, before radiation therapy. d Corticosteroid Dexamethasone 4 mg oral or IV Use as prophylactic therapy. Once daily on days of first 5 radiation therapy fractions, before radiation therapy. Low: Brain, head and neck, thorax, pelvis e 5-HT 3 receptor antagonist f Ondansetron 8 mg oral or 8 mg oral dissolving tablet, or 8 mg oral soluble film or 8 mg or 0.15 mg/kg IV Use as rescue therapy. g Granisetron 2 mg oral or 1 mg or 0.01 mg/kg IV Use as rescue therapy. g Corticosteroid Dexamethasone For brain, if not already taking corticosteroid, 4 mg oral or IV; for other anatomic regions, 4 mg oral or IV Use as rescue therapy. Titrate up as needed to maximum of 16 mg oral or IV daily. g Dopamine receptor antagonist h Prochlorperazine 5–10 mg oral or IV Use as rescue therapy. Titrate up as needed to maximum of 3–4 administrations daily. g Metoclopramide 5–20 mg oral or IV Use as rescue therapy. Titrate up as needed to maximum of 3–4 administrations daily. g Table 5. Antiemetic Administration in Adults by Radiation Therapy Risk Category (cont'd)

Articles in this issue

Archives of this issue

view archives of ASCO GUIDELINES Bundle - Antiemetics (CINV)