Issue link: https://eguideline.guidelinecentral.com/i/84987
Treatment ÎNormal and slow transit constipation are generally managed with medications; surgery is necessary for a minority of patients with slow transit constipation. ÎFunctional defecatory disorders are treated primarily with pelvic floor retraining using biofeedback therapy. ÎLactulose is effective at improving stool frequency and stool consistency in patients with CC. (A) ÎPsyllium (eg, Metamucil® patients with CC. (B) , Konsyl® ) increases stool frequency in ÎPolyethylene glycol is effective at improving stool frequency and stool consistency in patients with CC. (A) Notes: ▶ There are insufficient data to make a recommendation about the efficacy of calcium polycarbophil (eg, Perdiem Fiber Therapy® (eg, Citrucel® ▶ There are insufficient data to make a recommendation about the effectiveness of milk of magnesia or of stimulant laxatives in patients with CC. (B) be inferior to psyllium for improvement in stool frequency. (B) ÎLubiprostone (Amitiza® frequency and consistency in CC and IBS-C patients. (A) ÎLinaclotide (LinzessTM ), bran and stool softeners in patients with CC. Stool softeners may , FiberCon® ), methylcellulose ▶ There are insufficient data to make a recommendation about the effectiveness of herbal supplements, alternative treatments, lubricants or combination laxatives. (C) ) improves straining effort and increases stool ) increases complete spontaneous bowel movement frequency in patients with chronic idiopathic constipation and IBS-C. 8