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Lower Extremity Peripheral Artery Disease

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21 Table 31. Therapy for CLI: Findings That Prompt Consideration of Surgical or Endovascular Revascularization Findings That Favor Consideration of Surgical Revascularization Examples Factors associated with technical failure or poor durability with endovascular treatment Lesion involving common femoral artery, including origin of deep femoral artery Long segment lesion involving the below- knee popliteal and/or infrapopliteal arteries in a patient with suitable single-segment autogenous vein conduit Diffuse multilevel disease that would require endovascular revascularization at multiple anatomic levels Small-diameter target artery proximal to site of stenosis or densely calcified lesion at location of endovascular treatment Endovascular treatment likely to preclude or complicate subsequent achievement of in-line blood flow through surgical revascularization Single-vessel runoff distal to ankle Findings That Favor Consideration of Endovascular Revascularization Examples The presence of patient comorbidities may place patients at increased risk of perioperative complications from surgical revascularization. In these patients, an endovascular-first approach should be used regardless of anatomy Patient comorbidities, including coronary ischemia, cardiomyopathy, congestive heart failure, severe lung disease, and chronic kidney disease Patients with rest pain and disease at multiple levels may undergo a staged approach as part of endovascular-first approach In-flow disease can be addressed first, and out-flow disease can be addressed in a staged manner, when required, if clinical factors or patient safety prevent addressing all diseased segments at one setting. Patients without suitable autologous vein for bypass grafts Some patients have had veins harvested for previous coronary artery bypass surgery and do not have adequate remaining veins for use as conduits. Similarly, patients may not have undergone prior saphenous vein harvest, but available vein is of inadequate diameter.

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