Percutaneous Transluminal Angioplasty (PTA)
ÎFor patients undergoing peripheral artery PTA with or without stenting, the ACCP recommends long-term aspirin or clopidogrel (1-A).
ÎFor patients undergoing peripheral artery PTA with stenting, the ACCP suggests single rather than dual antiplatelet therapy (2-C).
Values and preferences: Patients who place a high value on an uncertain reduction in the risk of limb loss and a relatively low value on avoiding a definite increased risk of bleeding are more likely to choose to use dual antiplatelet therapy.
Bypass Graft Surgery
ÎFollowing peripheral artery bypass graft surgery the ACCP recommends long-term continuation of either aspirin or clopidogrel over no antithrombotic treatment (both 1-A).
ÎThe ACCP recommends single antiplatelet therapy over antiplatelet therapy and warfarin (1-B).
ÎIn patients undergoing below-knee bypass graft surgery with prosthetic grafts, the ACCP suggests clopidogrel plus aspirin over aspirin alone for 1 year (2-C). For all other bypass graft patients, the ACCP suggests single over dual antiplatelet therapy (2-B).
Carotid Stenosis
ÎFor persons with asymptomatic carotid stenosis, the ACCP suggests aspirin over no aspirin therapy (2-B).
ÎIn patients with symptomatic carotid stenosis (including recent carotid endarterectomy), the ACCP recommends long-term antiplatelet therapy with clopidogrel or aspirin/extended-release dipyridamole or aspirin over no antiplatelet therapy (1-A). The ACCP suggests either clopidogrel or aspirin/extended-release dipyridamole over aspirin (2-B).
