Abbreviations ALK, anaplastic lymphoma kinase gene; ASCO, American Society of Clinical Oncology; BSA, body-surface area; ECOG, Eastern Cooperative Oncology Group; EGFR, epidermal growth factor receptor; IHC, immunohistochemistry; NSCLC, non–small-cell lung cancer; OS, overall survival; PS, performance status; RCT, randomized clinical trial; TKI, tyrosine kinase inhibitor
Sources Azzoli CG, Temin S, Aliff T, et al. 2011 Focused update of 2009 American Society of Clinical Oncology clinical practice guideline update on chemotherapy for stage IV non–small-cell
lung cancer. J Clin Oncol. 2011;29(28):3825-3831. Available at: http://jco.ascopubs.org/cgi/ doi/10.1200/JCO.2010.34.2774
Azzoli CG, Baker S Jr, Temin S, et al. American Society of Clinical Oncology clinical practice guideline update on chemotherapy for stage IV non–small-cell lung cancer. J Clin Oncol. 2009; 27(36):6251-6266.
Keedy VL, Temin S, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: epidermal growth factor receptor (EGFR) mutation testing for patients with advanced non–small-cell lung cancer considering first-line EGFR tyrosine kinase inhibitor therapy. J Clin Oncol. 2011;29(15):2121-2127.
Disclaimer This resource is a practice tool for physicians based on an ASCO®
guideline and this tool are not intended to substitute for the independent professional judgment of the treating physician. Practice guidelines do not account for individual variation among patients and may not reflect the most recent evidence. This tool does not recommend any particular product or course of medical treatment. Use of the practice guideline and this resource is voluntary. The full practice guideline and additional information are available at http://www.asco.org/guidelines.
practice guideline. The practice Copyright © 2012 by American Society of Clinical Oncology® . All rights reserved. NSC051202p
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