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Figure 2. The Diabetes Epidemic: Global Projections, 2010-2030 Reprinted with permission from: International Diabetes Federation. IDF Diabetes Atlas, 5th ed. Brussels, Belgium: International Diabetes Federation, 2011. Figure 3. Main Pathophysiological Defects in T2DM Adapted from: Inzucchi SE, Darwin RS. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011. 1