ASCO GUIDELINES Bundle

Cervical Cancer Prevention

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In Limited Resource Settings Recommendation B1a ➤ Public health authorities, ministries of health, and primary care providers should vaccinate girls as early as possible, starting at 9 years through 14 years of age (Strong Recommendation; EB-H). Recommendation B2a ➤ For girls starting at 9 years of age who are immune competent, a two dose regimen is recommended (Moderate Recommendation; EB-I). Recommendation B2b ➤ The interval between the doses should be at least 6 months and may be up to 12–15 months (6 months: Strong Recommendation; EB-H, 12–15 months: Moderate Recommendation; EB-L). Recommendation B3 ➤ If there are sufficient resources remaining after vaccinating high-priority populations with an adequate target (minimum recommended coverage is ≥50% with two doses, with a target of 80%), for females who have received one dose and are more than 14 years of age, public health authorities may provide additional doses/complete the series up to 26 years of age (Moderate Recommendation; EB-I). Recommendation B4 a ➤ For prevention of cervical cancer in limited resource settings where vaccine coverage of girls is ≥50%, vaccination of boys is NOT recommended. • For prevention of cervical cancer, if there is low vaccine coverage of the priority female target population (<50%) in limited resource settings, then vaccination may be extended to boys (Moderate Recommendation; EB-I). In Basic Resource Settings Recommendation C1 ➤ Public health authorities, ministries of health, and primary care providers should vaccinate girls in the priority target age group starting as early as possible through 14 years of age (Strong Recommendation; EB-H). Recommendation C2a ➤ For girls starting at 9 years of age who are immune competent, a two- dose regimen is recommended (Moderate Recommendation; EB-I). Prevention

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