ASCO GUIDELINES Bundle

Invasive Cervical Cancer

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15 Enhanced Maximal Pelvic RT plus concurrent low-dose platinum-based chemotherapy plus brachytherapy Adjuvant hysterectomy is an option only if residual disease aer chemoRT (EB, H, S) Pelvic RT plus concurrent low-dose platinum-based chemotherapy plus brachytherapy Adjuvant hysterectomy is an option only if residual disease aer chemoRT (EB, H, S) Pelvic RT plus brachytherapy plus concurrent low-dose platinum-based chemotherapy (in some cases extended- field RT) and/or palliative care (EB, H, S) RT + brachytherapy ± concurrent low- dose platinum-based chemotherapy (may offer systemic adjuvant chemotherapy) (EB, I, W) Pelvic RT plus brachytherapy plus concurrent low-dose platinum-based chemotherapy (in some cases extended- field RT) and/or palliative care (options before palliative care alone include: RT boost, salvage surgery, or chemotherapy) (EB/CB, H, S) RT + brachytherapy ± concurrent low- dose platinum-based chemotherapy (may offer systemic adjuvant chemotherapy) (EB, I, W) Chemotherapy ± individualized RT and/or palliative care (EB, H, S) Chemotherapy ± bevacizumab ± individualized RT and/or palliative care (EB, H, S)

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