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Diabetic Foot Infection

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Abbreviations ABI, ankle-brachial index; C&S, culture and sensitivity; CPK, creatine phosphokinase; DFI, diabetic foot infection; DFO, diabetic foot osteomyelitis; ESBL, extended-spectrum β-lactamase; FDA, US Food and Drug Administration; GPC, Gram-positive cocci; GRADE, Grading of Recommendations Assessment, Development and Evaluation; IDSA, Infectious Diseases Society of America; IV, intravenous; IWGDF, International Working Group on the Diabetic Foot; MIC, minimum inhibitory concentration; MRI, magnetic resonance imaging; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive S. aureus; PEDIS, perfusion, extent, depth, infection, sensation (IWGDF research scoring); PO, oral; prn, as needed; PTB, probe to bone; qid, four times a day; RCT, randomized controlled trial; SIRS, systemic inflammatory response syndrome; tid, three times a day Source Lipsky BA, Berendt AR, Cornia PB, Pile JC, Peters EJG, Armstrong DG, Deery HG, Embil JM, Joseph WS, Karchmer AW, Pinzur MS, Senneville E. 2012 Infectious Diseases Society of America Clinical Practice Guideline for the Diagnosis and Treatment of Dia- betic Foot Infections. Clinical Infectious Diseases 2012;54(12):132–173. Disclaimer This Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. This Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. The ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aſter consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Tables in this guideline provide a concise summary; they should be used in the context of all of the evidence and recommendations made in the full guideline. PRINTCODE 5740 Executive Drive Suite 218 Baltimore, MD 21228 TEL: 410-869-3332 • FAX: 410-744-2150 For additional copies: Copyright © 2012 All rights reserved

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