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Potential Contraindications IOP Reduction
a
FDA Pregnancy
Safety Category
b
• Macular edema
• History of herpetic keratitis
• Active uveitis
25%–33% C
• Chronic obstructive pulmonary disease
(nonselective)
• Asthma (nonselective)
• CHF
• Bradycardia
• Hypotension
• Greater than first-degree heart block
20%–25% C
• Monoamine oxidase inhibitor therapy
• Infants and children <2 years
20%–25% B
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