Antiretroviral Agents in HIV-1

Antiretroviral Agents in HIV

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3-6 Months ✔ 2 Every ✔ 3 6 Months Every 12 Months Every In clinically stable patients with suppressed viral load, CD4 count can be monitored every 6-12 months Treatment Failure ✔ ✔ ✔ CCR5 antagonist- based regimen CCR5 antagonist or for failure of if considering ✔ Clinically Indicated ✔ ✔ ✔ ✔ ✔ ✔ ✔ measurement if abnormal at last ✔ if normal at last measurement measurement ✔ if abnormal at last ✔ if on TDF8 ✔ 6 Serum Na, K, HCO3 7 8 ✔ if normal at last measurement ✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔ For patients with renal disease, consult "Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America." monitoring phosphorus while on TDF; determination of renal function should include estimation of creatinine clearance using Cockcroft-Gault equation or estimation of glomerular filtration rate based on MDRD equation. , Cl, BUN, creatinine, glucose (preferably fasting); some experts suggest More frequent monitoring may be indicated for patients with increased risk of renal insufficiency, such as patients with diabetes, hypertension, etc. 23

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