Elimination
Expected to undergo catabolism to its constituent amino acids, with subsequent recycling of the amino acids in the body pool
Serum/ Half-life
3.8 hrs
Storage
Store at room temperature (up to 25ºC or 77ºF).
Reconstituted solution should be stored under refrigeration at 2ºC-8ºC (36ºF-46ºF) and used within 24 hours.
Adverse Events
▶ Local injection site reactions in almost 100% of patients (pain, erythema, induration, nodules and cysts, pruritus, ecchymosis)
▶ Increased bacterial pneumonia ▶ Hypersensitivity reaction (< 1%)— symptoms may include rash, fever, nausea, vomiting, chills, rigors, hypotension, or elevated serum transaminases; rechallenge is NOT recommended
Serum/Half-life 14-18 hrs
Elimination CYP3A4 substrate
Adverse Events
▶ Abdominal pain ▶ Cough ▶ Dizziness ▶ Musculoskeletal symptoms ▶ Pyrexia ▶ Rash ▶ Upper respiratory tract infections ▶ Hepatotoxicity ▶ Orthostatic hypotension
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