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Disclaimer is Guideline attempts to define principles of practice that should produce high-quality patient care. It is applicable to specialists, primary care, and providers at all levels. is Guideline should not be considered exclusive of other methods of care reasonably directed at obtaining the same results. e ultimate judgment concerning the propriety of any course of conduct must be made by the clinician aer consideration of each individual patient situation. Neither IGC, the medical associations, nor the authors endorse any product or service associated with the distributor of this clinical reference tool. Abbreviations AmB, amphotericin B; CNS, central nervous system; CVC, central venous catheters; HIV, human immunodeficiency virus; ICU, intensive care unit Source Pappas PG, Kauffman CA, Andes DR, Clancy CJ, Marr KA, Ostrosky-Zeichner L, Reboli AC, Schuster MG, Vazquez JA, Walsh TJ, Zaoutis TE, Sobel JD. Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2016 Feb 15;62(4):e1-e50. 106 Commerce Street, Suite 105 Lake Mary, FL 32746 TEL: 407.878.7606 • FAX: 407.878.7611 Order additional copies at Copyright © 2016 All rights reserved Table 2. Approach And Implications to Rating the Quality of Evidence and Strength of Recommendations Using the GRADE 2 Methodology Strong Weak Population Most people in this situation would want the intervention, and only a small proportion would not. e majority of people in this situation would want the intervention, but many would not. Health care workers Most people should receive the recommended course of action. Be more prepared to help patients to make a decision that is consistent with the patient's own values/decision aids and shared decision making. Policy Makers e recommendation can be adopted as a policy in most situations. ere is a need for substantial debate and involvement of stakeholders. Unrestricted use of the figure granted by the U.S. GRADE Network IDSACAN16013a

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