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Differentiated Thyroid Cancer

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DTC: Long-Term Management and Advanced Cancer Management 14 Figure 2. Clinical Decision-making and Management Recommendations in ATA Low Risk Differentiated Thyroid Cancer Patients That Have Undergone Less than Total Thyroidectomy (Lobectomy or Lobectomy with Isthmusectomy) Initial Therapy Lobectomy (R35) RAI Remnant Ablation Not Routinely Recommended (R38B) Evaluation of Post-Operative Disease Status • Consider post-op serum thyroglobulin (R50B, R50C) • Neck ultrasound (thyroid, central and lateral neck compartments) should be considered if not performed properatively Initial TSH Goal 0.5-2 mU/L (R59E) Evalutation Response to Therapy • Neck US (R65) • Consider Tg testing (R62B, R64) Excellent Response to Therapy • Primary follow-up with clinical exam and non-stimulated Tg (R64) • TSH goal 0.5-2.0 mU/L (R70E, Table 8) • Non-stimulated Tg 12-24 month intervals (R62C) • Periodic US examinations (R65) Biochemical Incomplete (rising serum Tg), Structural Incomplete, or Indeterminate Response See text for guidance

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